New way to make low-cost and long-lasting vaccines

New way to make low-cost and long-lasting vaccines

New way to make low-cost and long-lasting vaccines

Mexico City: Scientists from Mexico have invented a new vaccine-making technique that will be used to develop low-cost vaccines that can be safe for long periods of time at normal temperatures.Apart from other dumb issues with vaccines, one of the major problems is that they have to be kept in a very cold environment. The vaccine also loses its usefulness for a few days to just a few months if its cooling is reduced or additional heat is added, which can be used to cause harm rather than benefit. Vaccine inflation is another matter in its place.

According to one estimate, 80% of the total vaccine cost is spent on cooling arrangements only. That is, if the cost is somehow reduced then the cost of vaccine of Rs 1000 can be reduced to Rs 200.
Combining all these issues together, experts at the Institute for Cellular Physiology at the National Autonomous University of Mexico have invented a new vaccine-making method that is quite unique.

They adopted a strategy that uses insects to attack insects and maintain their existence for a long time in an open environment. For this purpose, viruses use a protein called "poly-headrin", which, when in unfavorable conditions, forms a pen (crystal) around the virus that protects it from severe weather conditions.

This protein is so hard to believe that even if conditions do not agree for years, it does not allow the virus to be destroyed. During their research, scientists discovered that the first 110 amino acids of polyhedron protein have the potential to form protective crystals around the virus. That is, if these proteins were made part of the vaccines, they would be safe for a long time, without being kept in an extremely cold environment.

During experiments on mice it was found that when a chain containing 110 amino acids of polyadenidine was attached to the vaccine molecules, the effectiveness of the vaccine increased and the small amount of it made the immune system stronger. On the other hand, the vaccine was kept at a normal temperature for one year; and when mice were used again, the efficacy remained the same.

It is important to note that the vaccine is usually very weak in our body's immune system due to the vaccine, which has to be added with the vaccine to supplement it. With polyhedron it will not be needed.

Currently, this technique is at an early stage that will require global approval to go through various stages of human trials, but in view of its usefulness, it is expected that this technique will soon be approved for human trials and other stages. ۔

The results of this research have been published in the latest issue of Research Journal "BMC Biotechnology".